Head-to-Head, PFSN Grades, and Prediction for College Football Week 10

An uber-important matchup between the Tennessee Volunteers and the Oklahoma Sooners is slated for Saturday night under the lights at Neyland Stadium.

Both teams enter Saturday with two losses in SEC play and are most likely not going to make the conference championship game. Yet both teams are still very much in the mix for the College Football Playoffs, and both still have plenty to play for.

Our Tennessee vs. Oklahoma prediction delivers the essential game information, complete historical series records, and exclusive PFSN player evaluations and team ratings.

Tennessee vs. Oklahoma Details

• Date: Saturday, Nov. 1, 2025
• Game time: 7:30 p.m. ET
• Location: Neyland Stadium | Knoxville, Tennessee
• Predicted weather at kick: 55 degrees, partly cloudy, 2 mph winds
• How to watch: ABC

Tennessee vs. Oklahoma Head-to-Head Record

This matchup has happened only five times in each program’s history, due to Oklahoma joining the SEC in 2024. Even with the small sample size, the games have been highly contested.

The Volunteers got the better of the Sooners last season in a defensive slugfest, winning 25-15 in Norman.

Back in 2015, Sooner quarterback Baker Mayfield threw an 18-yard touchdown pass to Sterling Shepard in double overtime to knock off the Volunteers 31-24 in an all-time great game.

Oklahoma leads the all-time series 3-2, with the total points scored in the series also favoring Oklahoma, 106 to Tennessee’s 100.

Tennessee vs. Oklahoma Grades

PFSN College OFFi

• Tennessee: 88.3 (B+)
• Oklahoma: 76.9 (C)

PFSN College DEFi

• Tennessee: 76.2 (C)
• Oklahoma: 95.5 (A)

PFSN College OLi

• Tennessee: 85.6 (B)
• Oklahoma: 78.2 (C+)

PFSN College QBi

• Joey Aguilar, Tennessee: 83.6 (B)
• John Mateer, Oklahoma: 77.9 (C+)

PFSN College RBi

• DeDean Bishop, Tennessee: 83.2 (B)
• Tory Blaylock, Oklahoma: 72.3 (C-)

PFSN College WRi

• Chris Brazzell II, Tennessee: 82 (B-)
• Isaiah Sategna III, Oklahoma 79.8 (C+)

PFSN College TEi

• Miles Kitselman, Tennessee: 76.1 (C)
• Jaren Kanak, Oklahoma: 80.6 (B-)

PFSN College EDGEi

• Joshua Josephs, Tennessee: 78.9 (C+)
• R Mason Thomas, Oklahoma: 81.4 (B-)

PFSN College DTi

• Dominic Bailey, Tennessee: 78.7 (C+)
• David Stone, Oklahoma: 81.9 (B-)

PFSN College LBi

• Arion Carter, Tennessee: 77.5 (C+)
• Kip Lewis, Oklahoma: 72.2 (C-)

PFSN College CBi

• Colton Hood, Tennessee: 90.5 (A-)
• Jacobe Johnson, Oklahoma: 81.5 (B-)

PFSN College SAFi

• Montrell Bandy, Tennessee: 80.1 (B-)
• Jaydan Hardy, Oklahoma: 76.6 (C)

Tennessee vs. Oklahoma Prediction

Tennessee head coach Josh Huepel will be coaching against his alma mater for only the second time in his career on Saturday. Huepel, a former All-American quarterback at Oklahoma and Heisman runner-up in 1999, is one of the best players to ever wear an Oklahoma jersey.

Tennessee quarterback Joey Aguilar will be looking to channel his best Huepel impersonation against Oklahoma.

In the Volunteers’ two losses to Georgia and Alabama, Aguilar got off to hot starts but tapered off as the games went on. That can’t happen for Aguilar, and especially can’t happen for the Tennessee offense on Saturday.

Tennessee’s weakness is its defense, which has been inconsistent at times. The Volunteers are giving up an average of 401.5 yards per game in conference play. In their Week 3 loss to Georgia, they surrendered 502 total yards.

They also struggle at cornerback due to injuries, and whoever finds themselves on the outside this week needs to come up big against an Oklahoma offense led by John Mateer.

Since Mateer’s thumb injury a few weeks ago, he hasn’t looked like the same player. He’s struggling to get through reads, and the run game and offensive line aren’t doing him any favors.

Last week against Ole Miss, Oklahoma found some success running the ball for the first time all year with Xavier Robinson. However, the Sooner run game is still a major issue. Oklahoma does have a dynamic duo in Isaiah Sategna III and Jaren Kanak that will pose problems for Tennessee.

Saturday night is a matchup of weakness versus weakness and strength versus strength, as both teams excel in areas where the other struggles.

The Volunteers rank sixth nationally, averaging 510.1 yards per game on offense, while Oklahoma ranks fifth in scoring defense, allowing just 12.5 points per game. Conversely, the Volunteers give up 30.9 points per game, and Oklahoma has only allowed more than 26 points once against a Power 4 opponent this season.

The key to the game is whether Oklahoma’s defense can hold up against Tennessee’s explosive offense. The Volunteers should manage on defense against an Oklahoma unit that struggles to run the ball.

Neyland at night is no joke and could be the X factor. Oklahoma’s offensive line likely won’t contain Dominic Bailey and Joshua Josephs, and Tennessee should be able to fluster Mateer, similar to how Texas did.

Chris Brazzell II will be a difference-maker outside, and Oklahoma can’t keep Tennessee off the scoreboard forever. Tennessee’s defense will do just enough against the Oklahoma offense, which can’t run the ball and has struggled post-Mateer injury.

This game could come down to a couple of key plays at the end. Neyland and Tennessee’s explosive offense will prevail in this College Football Playoff elimination matchup, securing Huepel’s second career victory against his alma mater.

Prediction: Tennessee 31, Oklahoma 27