Napoli announce Rasmus Hojlund
Napoli aim to keep their perfect start going with Rasmus Hojlund, Kevin De Bruyne and Scott McTominay, as Fiorentina seek their first win with Moise Kean and Edin Dzeko.
It kicks off at the Stadio Artemio Franchi at 19.45 UK time (18.45 GMT).
You can follow all the build-up and action as it happens from today’s three Serie A games on the Liveblog.
Where to watch Fiorentina vs. NapoliÂ
Tonight’s match will be shown live in the UK on DAZN. Supporters in the USA will be able to tune in through Paramount+.
Antonio Conte won the Scudetto last term and started this season in similarly strong fashion, beating Sassuolo and Cagliari, but the latter was only achieved deep into stoppages.
Injuries are piling up, with Amir Rrahmani joining David Neres, Miguel Gutierrez and Romelu Lukaku on the absentee list, so Sam Beukema gets his first start since the move from Bologna.
Hojlund is surprisingly launched straight into the starting XI after his big transfer from Manchester United, so Lorenzo Lucca drops to the bench.
Fiorentina have stuttered so far under Stefano Pioli, battling through a Conference League play-off to qualify for that tournament, then held to two Serie A draws by Cagliari and Torino.
Albert Gudmundsson and Christian Kouame are not fully fit, so Dzeko is preferred to Roberto Piccoli as the strike partner for Kean.
New signings Hans Nicolussi Caviglia and Tariq Lamptey are on the bench.
Napoli ultras groups boycotted this trip in protest at the number of tickets they were assigned, as space is limited with the stadium undergoing reconstruction work.
Fiorentina vs. Napoli line-ups
Fiorentina: De Gea; Comuzzo, Pongracic, Ranieri; Dodo, Sohm, Fagioli, Mandragora, Gosens; Dzeko, Kean
Napoli: Milinkovic-Savic; Di Lorenzo, Beukema, Buongiorno, Spinazzola; Lobotka; Politano, Anguissa, De Bruyne, McTominay; Hojlund
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