Liverpool have had an unblemished start to the Premier League and Champions League this season after securing narrow victories against the likes of Arsenal, Atlético Madrid and most recently Everton.
First-half goals from Ryan Gravenberch and new signing Hugo Ekitiké were enough to see off their Merseyside rivals, even after Idrissa Gueye’s second-half goal looked like Everton may be able to mount a comeback.
After emerging victorious in the derby, Arne Slot was quizzed about how his team coped with a difficult run of fixtures: “This is also the reason why teams like us, Chelsea, all the ones that are playing in Europe need a squad like this, because you need to play so many games.”
The depth of Slot’s squad will be on full display in their opening League Cup game this week as he confirmed that five of the weekend’s starters will be absent from the fixture.
Five ruled out of Southampton League Cup clash
In his pre-match press conference, Slot confirmed that a number of players would be rotated when Liverpool face Will Still’s Southampton. The players that fans won’t be seeing on Tuesday night are Virgil Van Dijk, Ibrahima Konate, Mohamed Salah, Ryan Gravenberch and Dominik Szoboszlai.
Van Dijk, Salah, Szoboszlai and Konate have played the most minutes of any Liverpool outfield players this season, and Gravenberch has played the ninth most, which is likely why they are being rested against this poor-form Southampton side, with all five also playing three games in the space of six days last week.
Despite being one of the favourites to push for promotion this season, Southampton have had a poor start to life back in the Championship with only one win from their opening six games.
While it has not been confirmed by Slot, another player who could be rotated for Southampton is Goalkeeper Alisson. Last week, The Daily Mail’s Lewis Steele shared that new goalkeeper Giorgi Mamardashvili had been “pencilled in” for a debut in this fixture.
Predicted Liverpool XI vs Southampton
One of the biggest benefits of Liverpool’s big summer is that they have high-quality options on the bench when they need to rotate. When defensive changes have been made this season, it has been Joe Gomez or Waturo Endo who have filled in at centre-back, but it seems likely only the former will start there against Southampton. Gomez is likely to be paired with 18-year-old Giovanni Leoni, who arrived from Italian side Parma in the summer.
In midfield, Slot could start Endo and Curtis Jones. Jones had been out of the side due to an injury sustained before the international break, but he got minutes against Everton, suggesting he is ready to be reintroduced to the team.
Only three players have scored more than one goal for Liverpool this season, and with Gravenberch and Salah confirmed to be out of the lineup, they will need to come from elsewhere. This could be the perfect opportunity for Florian Wirtz to find his shooting boots and show fans why Liverpool spent so much on him.
Alternatively, Liverpool’s youngest-ever goalscorer, Rio Ngumoha, could be given a chance. His three appearances this season have only amounted to 20 minutes of game time, with the highlight being his late winner against Newcastle.
With Southampton’s poor form, trying out some of these lesser-used players will unlikely run much risk. Each of the players mentioned would find game time against Southampton valuable for different reasons, and the match may serve as the perfect opportunity for Slot to give them what they need.
Predicted Liverpool XI vs Southampton: Mamardashvili, Frimpong, Gomez, Leoni, Robertson, Jones, Endo, Wirtz, Chiesa, Isak, Ngumoha

